Научные статьи
Статьи за 2024 год
DIAGNOSIS AND TREATMENT OF KIDNEY TRANSPLANT REJECTION: A LITERATURE REVIEW
Автор: Saitkarim A. Abdugafarov, Mels N. Assykbayev, Gulnur D. Daniyarova, Sholpan Kh. Altynova, Saule T. Shaisultanova, Saltanat S. Rakhimzhanova, Yurii V. Pya, Almira M. Manatova
Introduction. Kidney transplantation is the only radical method of treating most terminal stages of chronic renal failure. Acute rejection of the transplanted kidney is one …
Management of Patients Following Heart Transplantation: Experience of the Heart Center in Astana
Автор: Gulzhan Myrzakhmetova, Svetlana Novikova, Sholpan Altynova, Saule Shaisultanova, Yuryi Pya
This clinical case describes a patient who was diagnosed with mitral valve prolapse in childhood. Subsequently, the patient was diagnosed with dilated cardiomyopathy with progressive …
Evaluation of the effect of kidney transplantation on cardiac activity in patients with chronic heart failure in the outcome of stage 5 chronic kidney disease
Автор: Saitkarim Abdugafarov, Mels Asykbayev, Gulzhan Myrzakhmetova, Svetlana Novikova, Gulnur Daniyarova, Saule Shaisultanova, Mirgul Bayanova, Yuri Pya
The main cause of death in patients with terminal forms of chronic renal failure, on renal replacement therapy, are cardiovascular diseases. Cardiovascular diseases also account …
Ethical aspects of Organ Transplantation in Kazakhstan. Literature review
Автор: Gulnur Daniyarova, Aruzhan Asanova, Aidos Bolatov, Vitaliy Sazonov, Yuriy Pya, Kamila Akzholova
Over the past 50 years, transplantation has evolved into a widely successful practice around the world. However, significant disparities exist between countries regarding access to …
Noninvasive Biomarkers for Allograft Rejection in Pediatric Kidney Transplantation
Автор: Vitaliy Sazonov, Azhar Zhailauova, Sholpan Altynova, Mirgul Bayanova, Gulnur Daniyarova, Aidos Bolatov, Yuriy Pya
Introduction: Kidney transplantation is recognized as the most effective treatment for children with end-stage renal disease (ESRD), providing significant improvements in quality of life and …
SINGLE-CENTER EXPERIENCE OF HEART TRANSPLANTATION AT THE HEART CENTER OF ASTANA
Автор: Pya Yuryi, Abdiorazova Aigerim A., Altynova Sholpan Kh., Myrzakhmetova Gulzhan Sh., Novikova Svetlana P., Goncharov Alexey Y., Yakhimovich Yana S., Daniyarova Gulnur D.
Background. Chronic heart failure is a major global health issue. As a complication of most cardiovascular diseases, it affects 4% of the population. Heart transplantation …
Kidney transplantation in children in the Republic of Kazakhstan
Автор: Sholpan Altynova, Saltanat Rakhimzhanova, Samat Issakov, Ardak Ainakulov, Gani Kuttymuratov, Aigerim Abdiorazova, Gulnur Daniyarova, Saule Shaisultanova, Aliya Sailybayeva, Yuriy Pya
The purpose of the research is to analyze the clinical experience of kidney transplantation in children with end-stage chronic renal failure carried out since the …
Genetic landscape and phenotypic spectrum of osteogenesis imperfecta in the Kazakhstani pediatric population
Автор: Mirgul Bayanova, Aigerim Abilova, Marzhan Rakhimzhanova, Assiya Bazenova, Lyazzat Nazarova, Dias Malik, Naanlep Matthew Tanko, Nursulu Altaeva & Aidos Bolatov
This study investigates the genetic landscape and phenotypic spectrum of osteogenesis imperfecta (OI) in the Kazakhstani pediatric population, focusing on 40 children diagnosed and treated …
Understanding Pediatric Kidney Transplant Rejection: Its Pathophysiology, Biomarkers, and Management Strategies
Автор: Yuliya Semenova, Mirgul Bayanova, Saltanat Rakhimzhanova, Sholpan Altynova, Aliya Sailybayeva, Aruzhan
End-stage kidney disease requires comprehensive management strategies to ensure patient survival and improve quality of life. Kidney transplantation remains the preferred treatment option, offering superior …
Examining a 12-year experience within Kazakhstan’s national heart transplantation program
Автор: Yuliya Semenova, Saule Shaisultanova, Altynay Beyembetova, Aruzhan Asanova, Aliya Sailybayeva, Svetlana Novikova, Gulzhan Myrzakhmetova & Yuriy Pya
Kazakhstan has one of the lowest heart transplantation (HTx) rates globally, but there are no studies evaluating the outcomes of HTx. This study aimed to …
Evaluation of liver transplantation services in Kazakhstan from 2012 to 2023
Автор: Yuliya Semenova, Altynay Beyembetova, Saule Shaisultanova, Aruzhan Asanova, Aliya Sailybayeva, Sholpan Altynova & Yuriy Pya
There is a scarcity of publications evaluating the performance of the national liver transplantation (LTx) program in Kazakhstan. Spanning from 2012 to 2023, it delves …
Influence of Genetic Polymorphisms in CYP3A5, CYP3A4, and MDR1 on Tacrolimus Metabolism after kidney transplantation
Автор: Mirgul Bayanova, Aida Zhenissova, Lyazzat Nazarova, Aizhan Abdikadirova, Malika Sapargalieyva, Dias Malik, Aidos Bolatov, Saitkarim Abdugafarov, Mels Assykbayev, Sholpan Altynova, Yuriy Pya
Kidney transplantation stands as the ultimate recourse for restoring vital organ functions, particularly in cases of end-stage kidney disease where alternative treatments, such as dialysis, …
NONINVASIVE DIAGNOSIS OF HEART REJECTION AS A PREDICTOR OF LONG-TERM TRANSPLANT SURVIVAL
Автор: Mirzakhmetova G.Sh., Novikova S.P., Yakhimovich Y.S., Bayanova M.F., Altynova Sh. Kh., Pya Y.V.
stract Background. Currently, in Kazakhstan, the issue of chronic heart failure is becoming increasingly relevant, with high mortality from the terminal stage of chronic heart …
Solid Organ Transplantation in Kazakhstan: A Review on Current Situation and Challenges
Автор: Yuryi Pya, Aigerim Abdiorazova, Sholpan Altynova, Gulnur Daniyarova, Aruzhan Asanova, Saule Shaysultanova
Transplantation is one of the important strategic directions of medicine in Kazakhstan, which has been intensively developing in recent years. Noteworthy progress is observed in …